γ-AApeptides–based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide

The abnormal folding and aggregation of functional proteins into amyloid is a typical feature of many age-related diseases, including Type II diabetes. Growing evidence has revealed that the prevention of aggregate formation in culprit proteins could retard the progression of amyloid diseases. Human...

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Detalles Bibliográficos
Autores principales: Bolarinwa, Olapeju, Li, Chunpu, Khadka, Nawal, Li, Qi, Wang, Yan, Pan, Jianjun, Cai, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952368/
https://www.ncbi.nlm.nih.gov/pubmed/31919432
http://dx.doi.org/10.1038/s41598-019-56500-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952368/
https://www.ncbi.nlm.nih.gov/pubmed/31919432
http://dx.doi.org/10.1038/s41598-019-56500-0

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