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γ-AApeptides–based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide
The abnormal folding and aggregation of functional proteins into amyloid is a typical feature of many age-related diseases, including Type II diabetes. Growing evidence has revealed that the prevention of aggregate formation in culprit proteins could retard the progression of amyloid diseases. Human...
Autores principales: | Bolarinwa, Olapeju, Li, Chunpu, Khadka, Nawal, Li, Qi, Wang, Yan, Pan, Jianjun, Cai, Jianfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952368/ https://www.ncbi.nlm.nih.gov/pubmed/31919432 http://dx.doi.org/10.1038/s41598-019-56500-0 |
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