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Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis

Technical problems intrinsic to the purification of preribosome intermediates have limited our understanding of ribosome biosynthesis in humans. Addressing this issue is important given the implication of this biological process in human disease. Here we report a preribosome purification and tagging...

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Detalles Bibliográficos
Autores principales: Nieto, Blanca, Gaspar, Sonia G., Moriggi, Giulia, Pestov, Dimitri G., Bustelo, Xosé R., Dosil, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952385/
https://www.ncbi.nlm.nih.gov/pubmed/31919354
http://dx.doi.org/10.1038/s41467-019-13990-w