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ALG-2 couples T cell activation and apoptosis by regulating proteasome activity and influencing MCL1 stability
T cell homeostasis is critical for the proper function of the immune system. Following the sharp expansion upon pathogen infection, most T cells die in order to keep balance in the immune system, a process which is controlled by death receptors during the early phase and Bcl-2 proteins in the later...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952393/ https://www.ncbi.nlm.nih.gov/pubmed/31919392 http://dx.doi.org/10.1038/s41419-019-2199-4 |