The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection

The emergence of drug-resistant influenza type A viruses (IAVs) necessitates the development of novel anti-IAV agents. Here, we target the IAV hemagglutinin (HA) protein using multivalent peptide library screens and identify PVF-tet, a peptide-based HA inhibitor. PVF-tet inhibits IAV cytopathicity a...

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Detalles Bibliográficos
Autores principales: Omi, Jumpei, Watanabe-Takahashi, Miho, Igai, Katsura, Shimizu, Eiko, Tseng, Ching-Yi, Miyasaka, Tomohiro, Waku, Tsuyoshi, Hama, Shinichiro, Nakanishi, Rieka, Goto, Yuki, Nishino, Yuri, Miyazawa, Atsuo, Natori, Yasuhiro, Yamashita, Makoto, Nishikawa, Kiyotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952414/
https://www.ncbi.nlm.nih.gov/pubmed/31919357
http://dx.doi.org/10.1038/s41467-019-13974-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952414/
https://www.ncbi.nlm.nih.gov/pubmed/31919357
http://dx.doi.org/10.1038/s41467-019-13974-w

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