Aberrant expression of S-SCAM causes the loss of GABAergic synapses in hippocampal neurons

The duplication and deletion mutations of the S-SCAM/MAGI-2 gene are associated with schizophrenia and infantile spasms, respectively. S-SCAM is a unique synaptic scaffolding protein that localizes to both excitatory and GABAergic synapses. However, consequences of aberrant S-SCAM expression on GABA...

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Detalles Bibliográficos
Autores principales: Shin, Seung Min, Skaar, Samantha, Danielson, Eric, Lee, Sang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952429/
https://www.ncbi.nlm.nih.gov/pubmed/31919468
http://dx.doi.org/10.1038/s41598-019-57053-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952429/
https://www.ncbi.nlm.nih.gov/pubmed/31919468
http://dx.doi.org/10.1038/s41598-019-57053-y

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