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In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans

Fanconi Anemia is a rare genetic disease associated with DNA repair defects, congenital abnormalities and infertility. Most of FA pathway is evolutionary conserved, allowing dissection and mechanistic studies in simpler model systems such as Caenorhabditis elegans. In the present study, we employed...

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Detalles Bibliográficos
Autores principales: Germoglio, Marcello, Valenti, Anna, Gallo, Ines, Forenza, Chiara, Santonicola, Pamela, Silva, Nicola, Adamo, Adele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952437/
https://www.ncbi.nlm.nih.gov/pubmed/31919410
http://dx.doi.org/10.1038/s41598-019-57096-1