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In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans
Fanconi Anemia is a rare genetic disease associated with DNA repair defects, congenital abnormalities and infertility. Most of FA pathway is evolutionary conserved, allowing dissection and mechanistic studies in simpler model systems such as Caenorhabditis elegans. In the present study, we employed...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952437/ https://www.ncbi.nlm.nih.gov/pubmed/31919410 http://dx.doi.org/10.1038/s41598-019-57096-1 |