Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization

Greyhounds recover more slowly from certain injectable anesthetics than other dog breeds. Previous studies implicate cytochrome P450 (CYP) 2B11 as an important clearance mechanism for these drugs and suggest Greyhounds are deficient in CYP2B11. However, no CYP2B11 gene mutations have been identified...

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Detalles Bibliográficos
Autores principales: Martinez, Stephanie E., Andresen, Marie C., Zhu, Zhaohui, Papageorgiou, Ioannis, Court, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952448/
https://www.ncbi.nlm.nih.gov/pubmed/31919457
http://dx.doi.org/10.1038/s41598-019-56660-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952448/
https://www.ncbi.nlm.nih.gov/pubmed/31919457
http://dx.doi.org/10.1038/s41598-019-56660-z

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