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Multifaceted Hi-C benchmarking: what makes a difference in chromosome-scale genome scaffolding?

BACKGROUND: Hi-C is derived from chromosome conformation capture (3C) and targets chromatin contacts on a genomic scale. This method has also been used frequently in scaffolding nucleotide sequences obtained by de novo genome sequencing and assembly, in which the number of resultant sequences rarely...

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Detalles Bibliográficos
Autores principales: Kadota, Mitsutaka, Nishimura, Osamu, Miura, Hisashi, Tanaka, Kaori, Hiratani, Ichiro, Kuraku, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952475/
https://www.ncbi.nlm.nih.gov/pubmed/31919520
http://dx.doi.org/10.1093/gigascience/giz158