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PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection

Cohesin is a chromatin-bound complex that mediates sister chromatid cohesion and facilitates long-range interactions through DNA looping. How the transcription and replication machineries deal with the presence of cohesin on chromatin remains unclear. The dynamic association of cohesin with chromati...

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Detalles Bibliográficos
Autores principales: Morales, Carmen, Ruiz-Torres, Miguel, Rodríguez-Acebes, Sara, Lafarga, Vanesa, Rodríguez-Corsino, Miriam, Megías, Diego, Cisneros, David A., Peters, Jan-Michael, Méndez, Juan, Losada, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952610/
https://www.ncbi.nlm.nih.gov/pubmed/31757807
http://dx.doi.org/10.1074/jbc.RA119.011099