Multi-Omics Integration Reveals Short and Long-Term Effects of Gestational Hypoxia on the Heart Development

Antenatal hypoxia caused epigenetic reprogramming of methylome and transcriptome in the developing heart and increased the risk of heart disease later in life. Herein, we investigated the impact of gestational hypoxia in proteome and metabolome in the hearts of fetus and adult offspring. Pregnant ra...

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Detalles Bibliográficos
Autores principales: Gao, Yu, Dasgupta, Chiranjib, Huang, Lei, Song, Rui, Zhang, Ziwei, Zhang, Lubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952773/
https://www.ncbi.nlm.nih.gov/pubmed/31835778
http://dx.doi.org/10.3390/cells8121608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952773/
https://www.ncbi.nlm.nih.gov/pubmed/31835778
http://dx.doi.org/10.3390/cells8121608

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