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Cytoplasmic Restriction of Mutated SOD1 Impairs the DNA Repair Process in Spinal Cord Neurons

Amyotrophic lateral sclerosis (ALS) caused by mutation of superoxide dismutase 1 (SOD1), affects various cellular processes and results in the death of motor neurons with fatal defects. Currently, several neurological disorders associated with DNA damage are known to directly induce neurodegenerativ...

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Detalles Bibliográficos
Autores principales: Li, Jiaojie, Song, Miyoung, Moh, Sanghyun, Kim, Heemin, Kim, Dae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952796/
https://www.ncbi.nlm.nih.gov/pubmed/31771229
http://dx.doi.org/10.3390/cells8121502