A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

Signalling by cyclic adenosine monophosphate (cAMP) occurs via various effector proteins, notably protein kinase A and the guanine nucleotide exchange factors Epac1 and Epac2. These proteins are activated by cAMP binding to conserved cyclic nucleotide binding domains. The specific roles of the effec...

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Detalles Bibliográficos
Autores principales: Xu, Yunjian, Schwede, Frank, Wienk, Hans, Tengholm, Anders, Rehmann, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952820/
https://www.ncbi.nlm.nih.gov/pubmed/31817822
http://dx.doi.org/10.3390/cells8121589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952820/
https://www.ncbi.nlm.nih.gov/pubmed/31817822
http://dx.doi.org/10.3390/cells8121589

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