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Non-Redundant and Overlapping Oncogenic Readouts of Non-Canonical and Novel Colorectal Cancer KRAS and NRAS Mutants

RAS oncogene family members are molecular switches of signaling pathways that control cell growth, proliferation, differentiation, and survival. In colorectal cancer, Kirsten-RAS (KRAS) and neuroblastoma-RAS (NRAS) are the commonly mutated isoforms. Activating mutations in RAS result in cellular tra...

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Detalles Bibliográficos
Autores principales: Alcantara, Krizelle Mae M., Malapit, Joshua Reginald P., Yu, Ryan Timothy D., Garrido, Jose Antonio Ma. G., Rigor, John Paul T., Angeles, Arlou Kristina J., Cutiongco-de la Paz, Eva Maria, Garcia, Reynaldo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952822/
https://www.ncbi.nlm.nih.gov/pubmed/31816869
http://dx.doi.org/10.3390/cells8121557