Cargando…
Non-Redundant and Overlapping Oncogenic Readouts of Non-Canonical and Novel Colorectal Cancer KRAS and NRAS Mutants
RAS oncogene family members are molecular switches of signaling pathways that control cell growth, proliferation, differentiation, and survival. In colorectal cancer, Kirsten-RAS (KRAS) and neuroblastoma-RAS (NRAS) are the commonly mutated isoforms. Activating mutations in RAS result in cellular tra...
Autores principales: | Alcantara, Krizelle Mae M., Malapit, Joshua Reginald P., Yu, Ryan Timothy D., Garrido, Jose Antonio Ma. G., Rigor, John Paul T., Angeles, Arlou Kristina J., Cutiongco-de la Paz, Eva Maria, Garcia, Reynaldo L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952822/ https://www.ncbi.nlm.nih.gov/pubmed/31816869 http://dx.doi.org/10.3390/cells8121557 |
Ejemplares similares
-
Phenotypic characterization of the novel, non-hotspot oncogenic KRAS mutants E31D and E63K
por: Angeles, Arlou Kristina J., et al.
Publicado: (2019) -
MicroRNA-92a promotes cell proliferation, migration and survival by directly targeting the tumor suppressor gene NF2 in colorectal and lung cancer cells
por: Alcantara, Krizelle Mae M., et al.
Publicado: (2019) -
The Novel Phosphatase Domain Mutations Q171R and Y65S Switch PTEN from Tumor Suppressor to Oncogene
por: Garrido, Jose Antonio Ma. G., et al.
Publicado: (2021) -
Identification and validation of mRNA 3′untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN
por: Roquid, Kenneth Anthony R., et al.
Publicado: (2019) -
NRAS and KRAS polymorphisms are not associated with hepatoblastoma susceptibility in Chinese children
por: Yang, Tianyou, et al.
Publicado: (2019)