JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses

Transforming growth factor-β (TGFβ) has both tumor-suppressive and tumor-promoting effects in breast cancer. These functions are partly mediated through Smads, intracellular transcriptional effectors of TGFβ. Smads form complexes with other DNA-binding transcription factors to elicit cell-type-depen...

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Detalles Bibliográficos
Autores principales: Sundqvist, Anders, Voytyuk, Oleksandr, Hamdi, Mohamed, Popeijus, Herman E., Bijlsma-van der Burgt, Corina, Janssen, Josephine, Martens, John W.M., Moustakas, Aristidis, Heldin, Carl-Henrik, ten Dijke, Peter, van Dam, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952832/
https://www.ncbi.nlm.nih.gov/pubmed/31766464
http://dx.doi.org/10.3390/cells8121481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952832/
https://www.ncbi.nlm.nih.gov/pubmed/31766464
http://dx.doi.org/10.3390/cells8121481

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