Identification of TRIM25 as a Negative Regulator of Caspase-2 Expression Reveals a Novel Target for Sensitizing Colon Carcinoma Cells to Intrinsic Apoptosis

Colorectal cancer (CRC) is one of the most common cancers that is characterized by a high mortality due to the strong metastatic potential of the primary tumor and the high rate of therapy resistance. Hereby, evasion of apoptosis is the primary underlying cause of reduced sensitivity of tumor cells...

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Detalles Bibliográficos
Autores principales: Nasrullah, Usman, Haeussler, Kristina, Biyanee, Abhiruchi, Wittig, Ilka, Pfeilschifter, Josef, Eberhardt, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952940/
https://www.ncbi.nlm.nih.gov/pubmed/31842382
http://dx.doi.org/10.3390/cells8121622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952940/
https://www.ncbi.nlm.nih.gov/pubmed/31842382
http://dx.doi.org/10.3390/cells8121622

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