Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins

Pin1 is one of the three known prolyl-isomerase types and its hepatic expression level is markedly enhanced in the obese state. Pin1 plays critical roles in favoring the exacerbation of both lipid accumulation and fibrotic change accompanying inflammation. Indeed, Pin1-deficient mice are highly resi...

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Detalles Bibliográficos
Autores principales: Inoue, Masa-Ki, Nakatsu, Yusuke, Yamamotoya, Takeshi, Hasei, Shun, Kanamoto, Mayu, Naitou, Miki, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Kushiyama, Akifumi, Asano, Tomoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952946/
https://www.ncbi.nlm.nih.gov/pubmed/31795496
http://dx.doi.org/10.3390/cells8121545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952946/
https://www.ncbi.nlm.nih.gov/pubmed/31795496
http://dx.doi.org/10.3390/cells8121545

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