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Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages

Stefin B (cystatin B) is an intracellular inhibitor of cysteine cathepsins and mutations in the stefin B gene, resulting in the development of Unverricht–Lundborg disease, which is a form of myoclonic epilepsy. It was suggested that a key mechanism behind stefin B-mediated disease progression was im...

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Detalles Bibliográficos
Autores principales: Trstenjak Prebanda, Mojca, Završnik, Janja, Turk, Boris, Kopitar Jerala, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952955/
https://www.ncbi.nlm.nih.gov/pubmed/31766320
http://dx.doi.org/10.3390/cells8121476