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NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus

Aldosterone excess aggravates endothelial dysfunction in diabetes and hypertension by promoting the increased generation of reactive oxygen species, inflammation, and insulin resistance. Aldosterone activates the molecular platform inflammasome in immune system cells and contributes to vascular dysf...

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Detalles Bibliográficos
Autores principales: Ferreira, Nathanne Santos, Bruder-Nascimento, Thiago, Pereira, Camila André, Zanotto, Camila Zillioto, Prado, Douglas Silva, Silva, Josiane Fernandes, Rassi, Diane Meyre, Foss-Freitas, Maria Cristina, Alves-Filho, Jose Carlos, Carlos, Daniela, Tostes, Rita de Cássia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952964/
https://www.ncbi.nlm.nih.gov/pubmed/31817997
http://dx.doi.org/10.3390/cells8121595