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Extracellular Vesicles–Encapsulated MicroRNA-125b Produced in Genetically Modified Mesenchymal Stromal Cells Inhibits Hepatocellular Carcinoma Cell Proliferation

Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer and one of the prominent causes of cancer mortality, leading to approximately 780,000 deaths per year worldwide. Down-regulation of microRNA-125b (miR-125b) is a prognostic indicator in HCC patients. Conversely, over-ex...

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Detalles Bibliográficos
Autores principales: Baldari, Silvia, Di Rocco, Giuliana, Magenta, Alessandra, Picozza, Mario, Toietta, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952965/
https://www.ncbi.nlm.nih.gov/pubmed/31816923
http://dx.doi.org/10.3390/cells8121560