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Adjuvant Epigenetic Therapy of Decitabine and Suberoylanilide Hydroxamic Acid Exerts Anti-Neoplastic Effects in Acute Myeloid Leukemia Cells

Atypical epigenetic processes including histone acetylation and DNA methylation have been identified as a fundamental theme in hematologic malignancies. Such mechanisms modify gene expression and prompt, in part at least, the initiation and progression of several malignancies including acute myeloid...

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Detalles Bibliográficos
Autores principales: Abou Najem, Sonia, Khawaja, Ghada, Hodroj, Mohammad Hassan, Babikian, Patil, Rizk, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952979/
https://www.ncbi.nlm.nih.gov/pubmed/31766421
http://dx.doi.org/10.3390/cells8121480