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Aberrant Oligodendrogenesis in Down Syndrome: Shift in Gliogenesis?
Down syndrome (DS), or trisomy 21, is the most prevalent chromosomal anomaly accounting for cognitive impairment and intellectual disability (ID). Neuropathological changes of DS brains are characterized by a reduction in the number of neurons and oligodendrocytes, accompanied by hypomyelination and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953000/ https://www.ncbi.nlm.nih.gov/pubmed/31817891 http://dx.doi.org/10.3390/cells8121591 |