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Cellular Model of Endotoxin Tolerance in Astrocytes: Role of Interleukin 10 and Oxylipins

A phenomenon of endotoxin tolerance where prior exposure of cells to minute amounts of lipopolysaccharide (LPS) causes them to become refractory to a subsequent high-amount endotoxin challenge is well described for innate immune cells such as monocytes/macrophages, but it is still obscure for brain...

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Detalles Bibliográficos
Autores principales: Chistyakov, Dmitry V., Astakhova, Alina A., Azbukina, Nadezda V., Goriainov, Sergei V., Chistyakov, Viktor V., Sergeeva, Marina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953006/
https://www.ncbi.nlm.nih.gov/pubmed/31805746
http://dx.doi.org/10.3390/cells8121553