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Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline

Stroke increases neurogenesis in the adult dentate gyrus in the short term, however, long-term effects at the cellular and functional level are poorly understood. Here we evaluated the impact of an early stroke lesion on neurogenesis and cognitive function of the aging brain. We hypothesized that a...

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Detalles Bibliográficos
Autores principales: Kathner-Schaffert, Carolin, Karapetow, Lina, Günther, Madlen, Rudolph, Max, Dahab, Mahmoud, Baum, Eileen, Lehmann, Thomas, Witte, Otto W., Redecker, Christoph, Schmeer, Christian W., Keiner, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953020/
https://www.ncbi.nlm.nih.gov/pubmed/31861141
http://dx.doi.org/10.3390/cells8121654