GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice

Rheumatoid arthritis (RA) is characterized by the massive infiltration of various chronic inflammatory cells in synovia. In synovial fluid of patients with RA, M1 macrophages are dominant among all subtypes of macrophages, the mechanisms of macrophages polarization imbalance in RA has not been fully...

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Detalles Bibliográficos
Autores principales: Yang, Xuezhi, Li, Susu, Zhao, Yingjie, Li, Siyu, Zhao, Tianjiao, Tai, Yu, Zhang, Bingjie, Wang, Xinwei, Wang, Chun, Chen, Jingyu, Wang, Qingtong, Zhang, Lingling, Xu, Dexiang, Chang, Yan, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953022/
https://www.ncbi.nlm.nih.gov/pubmed/31818003
http://dx.doi.org/10.3390/cells8121596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953022/
https://www.ncbi.nlm.nih.gov/pubmed/31818003
http://dx.doi.org/10.3390/cells8121596

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