PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype

During tumorigenesis, macrophages are recruited by tumors and orientated towards a pro-tumoral phenotype. One of the main anti-tumoral immunotherapy consists of their re-polarization in an anti-tumoral phenotype. We have demonstrated that the inhibition of proprotein convertase 1/3 combined with TLR...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodet, Franck, Capuz, Alice, Ozcan, Bilgehan-Aybike, Le Beillan, Rémy, Raffo-Romero, Antonella, Kobeissy, Firas, Duhamel, Marie, Salzet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953035/
https://www.ncbi.nlm.nih.gov/pubmed/31766635
http://dx.doi.org/10.3390/cells8121490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953035/
https://www.ncbi.nlm.nih.gov/pubmed/31766635
http://dx.doi.org/10.3390/cells8121490

Ejemplares similares