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PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype

During tumorigenesis, macrophages are recruited by tumors and orientated towards a pro-tumoral phenotype. One of the main anti-tumoral immunotherapy consists of their re-polarization in an anti-tumoral phenotype. We have demonstrated that the inhibition of proprotein convertase 1/3 combined with TLR...

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Detalles Bibliográficos
Autores principales:	Rodet, Franck, Capuz, Alice, Ozcan, Bilgehan-Aybike, Le Beillan, Rémy, Raffo-Romero, Antonella, Kobeissy, Firas, Duhamel, Marie, Salzet, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953035/ https://www.ncbi.nlm.nih.gov/pubmed/31766635 http://dx.doi.org/10.3390/cells8121490

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