Cargando…

Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model

The low-density lipoprotein receptor-related protein 1 (LRP1) is a transmembrane receptor, mediating endocytosis and activating intracellular signaling cascades. LRP1 is highly expressed in the central nervous system (CNS), especially in oligodendrocyte precursor cells (OPCs). Previous studies have...

Descripción completa

Detalles Bibliográficos
Autores principales: Schäfer, Ina, Kaisler, Johannes, Scheller, Anja, Kirchhoff, Frank, Haghikia, Aiden, Faissner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953036/
https://www.ncbi.nlm.nih.gov/pubmed/31801252
http://dx.doi.org/10.3390/cells8121550