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Copresentation of BMP-6 and RGD Ligands Enhances Cell Adhesion and BMP-Mediated Signaling

We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and signaling responses which regulate the transdifferentiation of myoblasts into osteogenic cells. To immobilize BMP-6, t...

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Detalles Bibliográficos
Autores principales: Posa, Francesca, Grab, Anna Luise, Martin, Volker, Hose, Dirk, Seckinger, Anja, Mori, Giorgio, Vukicevic, Slobodan, Cavalcanti-Adam, Elisabetta Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953040/
https://www.ncbi.nlm.nih.gov/pubmed/31847477
http://dx.doi.org/10.3390/cells8121646