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Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential

For the production and bio-banking of differentiated derivatives from human pluripotent stem cells (hPSCs) in large quantities for drug screening and cellular therapies, well-defined and robust procedures for differentiation and cryopreservation are required. Definitive endoderm (DE) gives rise to r...

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Detalles Bibliográficos
Autores principales: Sahabian, Anais, Sgodda, Malte, Naujok, Ortwin, Dettmer, Rabea, Dahlmann, Julia, Manstein, Felix, Cantz, Tobias, Zweigerdt, Robert, Martin, Ulrich, Olmer, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953099/
https://www.ncbi.nlm.nih.gov/pubmed/31817235
http://dx.doi.org/10.3390/cells8121571