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Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential
For the production and bio-banking of differentiated derivatives from human pluripotent stem cells (hPSCs) in large quantities for drug screening and cellular therapies, well-defined and robust procedures for differentiation and cryopreservation are required. Definitive endoderm (DE) gives rise to r...
Autores principales: | Sahabian, Anais, Sgodda, Malte, Naujok, Ortwin, Dettmer, Rabea, Dahlmann, Julia, Manstein, Felix, Cantz, Tobias, Zweigerdt, Robert, Martin, Ulrich, Olmer, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953099/ https://www.ncbi.nlm.nih.gov/pubmed/31817235 http://dx.doi.org/10.3390/cells8121571 |
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