Therapeutic Opportunities with Pharmacological Inhibition of CD38 with Isatuximab

CD38 is a transmembrane glycoprotein with ectoenzymatic activity involved in regulation of migration, signal transduction, and receptor-mediated adhesion. CD38 is highly expressed on various malignant cells, including multiple myeloma (MM), and at relatively low levels in other tissues, making it a...

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Detalles Bibliográficos
Autores principales: Martin, Thomas G., Corzo, Kathryn, Chiron, Marielle, van de Velde, Helgi, Abbadessa, Giovanni, Campana, Frank, Solanki, Malini, Meng, Robin, Lee, Helen, Wiederschain, Dmitri, Zhu, Chen, Rak, Alexey, Anderson, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953105/
https://www.ncbi.nlm.nih.gov/pubmed/31779273
http://dx.doi.org/10.3390/cells8121522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953105/
https://www.ncbi.nlm.nih.gov/pubmed/31779273
http://dx.doi.org/10.3390/cells8121522

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