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MS CD49d(+)CD154(+) Lymphocytes Reprogram Oligodendrocytes into Immune Reactive Cells Affecting CNS Regeneration

The critical aspect in multiple sclerosis (MS) progression involves insufficient regeneration of CNS resulting from deficient myelin synthesis by newly generated oligodendrocytes (OLs). Although many studies have focused on the role of autoreactive lymphocytes in the inflammatory-induced axonal loss...

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Detalles Bibliográficos
Autores principales: Piatek, Paweł, Namiecinska, Magdalena, Domowicz, Małgorzata, Przygodzka, Patrycja, Wieczorek, Marek, Michlewska, Sylwia, Lewkowicz, Natalia, Tarkowski, Maciej, Lewkowicz, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953114/
https://www.ncbi.nlm.nih.gov/pubmed/31775315
http://dx.doi.org/10.3390/cells8121508