B-RAF(V600E) Inhibitor Dabrafenib Attenuates RIPK3-Mediated Necroptosis and Promotes Functional Recovery after Spinal Cord Injury

The receptor-interacting protein kinase 3 (RIPK3) is a key regulator of necroptosis and is involved in various pathologies of human diseases. We previously reported that RIPK3 expression is upregulated in various neural cells at the lesions and necroptosis contributed to secondary neural tissue dama...

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Detalles Bibliográficos
Autores principales: Sugaya, Takehiro, Kanno, Haruo, Matsuda, Michiharu, Handa, Kyoichi, Tateda, Satoshi, Murakami, Taishi, Ozawa, Hiroshi, Itoi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953123/
https://www.ncbi.nlm.nih.gov/pubmed/31817643
http://dx.doi.org/10.3390/cells8121582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953123/
https://www.ncbi.nlm.nih.gov/pubmed/31817643
http://dx.doi.org/10.3390/cells8121582

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