The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection

The Zika virus (ZIKV) non-structural protein 5 (NS5) plays multiple viral and cellular roles during infection, with its primary role in virus RNA replication taking place in the cytoplasm. However, immunofluorescence assay studies have detected the presence of ZIKV NS5 in unique spherical shell-like...

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Detalles Bibliográficos
Autores principales: Tan, Min Jie Alvin, Chan, Kitti Wing Ki, Ng, Ivan H. W., Kong, Sean Yao Zu, Gwee, Chin Piaw, Watanabe, Satoru, Vasudevan, Subhash G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953166/
https://www.ncbi.nlm.nih.gov/pubmed/31779251
http://dx.doi.org/10.3390/cells8121519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953166/
https://www.ncbi.nlm.nih.gov/pubmed/31779251
http://dx.doi.org/10.3390/cells8121519

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