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Engineering the interactions between a plant‐produced HIV antibody and human Fc receptors

Plants can provide a cost‐effective and scalable technology for production of therapeutic monoclonal antibodies, with the potential for precise engineering of glycosylation. Glycan structures in the antibody Fc region influence binding properties to Fc receptors, which opens opportunities for modula...

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Detalles Bibliográficos
Autores principales: Stelter, Szymon, Paul, Mathew J., Teh, Audrey Y.‐H., Grandits, Melanie, Altmann, Friedrich, Vanier, Jessica, Bardor, Muriel, Castilho, Alexandra, Allen, Rachel Louise, Ma, Julian K‐C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953194/
https://www.ncbi.nlm.nih.gov/pubmed/31301102
http://dx.doi.org/10.1111/pbi.13207