Novel immunomodulatory drugs and neo-substrates

Thalidomide, lenalidomide and pomalidomide are immunomodulatory drugs (IMiDs) effective in the treatment of multiple myeloma, myelodysplastic syndrome (MDS) with deletion of chromosome 5q and other hematological malignancies. Recent studies showed that IMiDs bind to CRBN, a substrate receptor of CRL...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Shaobing, Wang, Shichao, Song, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953231/
https://www.ncbi.nlm.nih.gov/pubmed/31938543
http://dx.doi.org/10.1186/s40364-020-0182-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953231/
https://www.ncbi.nlm.nih.gov/pubmed/31938543
http://dx.doi.org/10.1186/s40364-020-0182-y

Ejemplares similares