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Intein-mediated recombinant expression of monomeric B22Asp desB30 insulin
BACKGROUND: Insulin controls hyperglycemia caused by diabetes, and virtually all treatments require exogenous insulin. However, the product’s extensive post-translational modifications have hindered the manufacture of recombinant insulin. RESULT: Here we report a novel production method for a monome...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953245/ https://www.ncbi.nlm.nih.gov/pubmed/31918694 http://dx.doi.org/10.1186/s12896-020-0598-3 |