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Intein-mediated recombinant expression of monomeric B22Asp desB30 insulin

BACKGROUND: Insulin controls hyperglycemia caused by diabetes, and virtually all treatments require exogenous insulin. However, the product’s extensive post-translational modifications have hindered the manufacture of recombinant insulin. RESULT: Here we report a novel production method for a monome...

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Detalles Bibliográficos
Autores principales:	Zhang, Minmin, Zhang, Yunlong, Wu, Bingnan, Peng, Yanhao, Simair, Altaf Ahmed, Siegel, Geoffery W., Lu, Changrui, Chen, Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953245/ https://www.ncbi.nlm.nih.gov/pubmed/31918694 http://dx.doi.org/10.1186/s12896-020-0598-3

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