Isotalatizidine, a C(19)-diterpenoid alkaloid, attenuates chronic neuropathic pain through stimulating ERK/CREB signaling pathway-mediated microglial dynorphin A expression

BACKGROUND: Isotalatizidine is a representative C(19)-diterpenoid alkaloid extracted from the lateral roots of Aconitum carmichaelii, which has been widely used to treat various diseases on account of its analgesic, anti-inflammatory, anti-rheumatic, and immunosuppressive properties. The aim of this...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Shuai, Xia, Huan, Hu, Min, Chen, Chengjuan, Fu, Junmin, Shi, Gaona, Guo, Qinglan, Zhou, Yu, Wang, Wenjie, Shi, Jiangong, Zhang, Tiantai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953278/
https://www.ncbi.nlm.nih.gov/pubmed/31924228
http://dx.doi.org/10.1186/s12974-019-1696-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953278/
https://www.ncbi.nlm.nih.gov/pubmed/31924228
http://dx.doi.org/10.1186/s12974-019-1696-9

Ejemplares similares