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The antagonism of 6-shogaol in high-glucose-activated NLRP3 inflammasome and consequent calcification of human artery smooth muscle cells

BACKGROUND: Vascular calcification is the major reason for high mortality of cardiovascular complications for diabetes. Interleukin (IL)-1β has been implicated in this pathogenesis, but its precise role and clinical evidence have not been clearly identified. Hence, this study was aimed to investigat...

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Detalles Bibliográficos
Autores principales: Chen, Te-Chuan, Yen, Chia-Kung, Lu, Ying-Chen, Shi, Chung-Sheng, Hsieh, Rong-Ze, Chang, Shun-Fu, Chen, Cheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953308/
https://www.ncbi.nlm.nih.gov/pubmed/31938471
http://dx.doi.org/10.1186/s13578-019-0372-1