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Reduced GLP-1 response to a meal is associated with the CTLA4 rs3087243 G/G genotype

Although insulitis is the characteristic main feature of type 1 diabetes mellitus (T1DM), many aspects of β cell loss still remain elusive. Immune dysregulation and alterations in the dipeptidyl-peptidase-4-incretin system might have a role in disease development, but their connection is poorly unde...

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Detalles Bibliográficos
Autores principales: Zóka, András, Barna, Gábor, Nyírő, Gábor, Molnár, Ágnes, Németh, László, Műzes, Györgyi, Somogyi, Anikó, Firneisz, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953372/
https://www.ncbi.nlm.nih.gov/pubmed/31933538
http://dx.doi.org/10.5114/ceji.2019.89604