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Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment

Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal networks. This dysfunction emerges during early development, before a detectable behavioral readout, yet the cellular elements controlling the abnormal maturation are still unknown. Here, we address th...

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Detalles Bibliográficos
Autores principales: Chini, Mattia, Pöpplau, Jastyn A., Lindemann, Christoph, Carol-Perdiguer, Laura, Hnida, Marilena, Oberländer, Victoria, Xu, Xiaxia, Ahlbeck, Joachim, Bitzenhofer, Sebastian H., Mulert, Christoph, Hanganu-Opatz, Ileana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953432/
https://www.ncbi.nlm.nih.gov/pubmed/31733940
http://dx.doi.org/10.1016/j.neuron.2019.09.042