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Erythromyeloid progenitors give rise to a population of osteoclasts contributing to bone homeostasis and repair

The osteoclast is a multinucleated monocyte/macrophage lineage cell that degrades bone. Here we used lineage tracing studies, labeling cells expressing Cx3cr1, Csf1r, or Flt3 to identify the precursors of osteoclast in mice. We identified an erythromyeloid progenitor (EMP)-derived osteoclast precurs...

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Detalles Bibliográficos
Autores principales: Yahara, Yasuhito, Barrientos, Tomasa, Tang, Yuning J., Puviindran, Vijitha, Nadesan, Puviindran, Zhang, Hongyuan, Gibson, Jason, Gregory, Simon G., Diao, Yarui, Xiang, Yu, Qadri, Yawar J., Souma, Tomokazu, Shinohara, Mari L., Alman, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953622/
https://www.ncbi.nlm.nih.gov/pubmed/31907410
http://dx.doi.org/10.1038/s41556-019-0437-8