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Efficient dose-finding for drug combination studies involving a shift in study populations
This paper describes the design of an early phase, prospective trial evaluating the safety and tolerability of the combination of the histone deacetylase inhibitor, entinostat, in combination with capecitabine. The study consists of two parts; an initial phase evaluating the safety of the combinatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953647/ https://www.ncbi.nlm.nih.gov/pubmed/31938755 http://dx.doi.org/10.1016/j.conctc.2020.100519 |