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Efficient dose-finding for drug combination studies involving a shift in study populations

This paper describes the design of an early phase, prospective trial evaluating the safety and tolerability of the combination of the histone deacetylase inhibitor, entinostat, in combination with capecitabine. The study consists of two parts; an initial phase evaluating the safety of the combinatio...

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Detalles Bibliográficos
Autores principales:	Wages, Nolan A., Millard, Trish A., Dillon, Patrick M., Brenin, Christiana M., Petroni, Gina R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953647/ https://www.ncbi.nlm.nih.gov/pubmed/31938755 http://dx.doi.org/10.1016/j.conctc.2020.100519

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