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MEL Ameliorates Post-SAH Cerebral Vasospasm by Affecting the Expression of eNOS and HIF1α via H19/miR-138/eNOS/NO and H19/miR-675/HIF1α

Melatonin (MEL) has been demonstrated to exert a protective effect against subarachnoid hemorrhage (SAH), and nitric oxide (NO) has been shown to play an important role in the pathogenesis of vasospasm. This study aims to explore the underlying molecular mechanisms of MEL in the control of vasospasm...

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Detalles Bibliográficos
Autores principales: Hou, Guoqiang, Chen, Hongjin, Yin, Yuhua, Pan, Yaohua, Zhang, Xiaohua, Jia, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953775/
https://www.ncbi.nlm.nih.gov/pubmed/31927306
http://dx.doi.org/10.1016/j.omtn.2019.12.002