Cargando…

MEL Ameliorates Post-SAH Cerebral Vasospasm by Affecting the Expression of eNOS and HIF1α via H19/miR-138/eNOS/NO and H19/miR-675/HIF1α

Melatonin (MEL) has been demonstrated to exert a protective effect against subarachnoid hemorrhage (SAH), and nitric oxide (NO) has been shown to play an important role in the pathogenesis of vasospasm. This study aims to explore the underlying molecular mechanisms of MEL in the control of vasospasm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Guoqiang, Chen, Hongjin, Yin, Yuhua, Pan, Yaohua, Zhang, Xiaohua, Jia, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953775/ https://www.ncbi.nlm.nih.gov/pubmed/31927306 http://dx.doi.org/10.1016/j.omtn.2019.12.002

Ejemplares similares

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

eNOS expression and NO release during hypoxia is inhibited by miR-200b in human endothelial cells
por: Janaszak-Jasiecka, Anna, et al.
Publicado: (2018)

Heterozygous eNOS Deficient Mice as a Model to Examine the Effects of eNOS Haploinsufficiency on the Cerebral Circulation
por: Didion, Sean P.
Publicado: (2017)

mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022)

Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis
por: Choi, Seunghwan, et al.
Publicado: (2017)

A novel imidazolinone metformin‐methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF‐1α pathway
por: Nguyen, Huong, et al.
Publicado: (2021)

AB184. Icariside II induces NO production in human cavernous endothelial cells via the activation of eNOS by miR-155
por: Lei, Hongen, et al.
Publicado: (2015)

Association of genetic polymorphisms of eNOS with glaucoma
por: Liao, Qiong, et al.
Publicado: (2011)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling
por: Mu, Haiman, et al.
Publicado: (2019)

Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway
por: Guo, Jia Y, et al.
Publicado: (2011)

Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway
por: ZENG, ZHI, et al.
Publicado: (2015)

Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway
por: Zeng, Zhi, et al.
Publicado: (2023)

Data on eNOS T786 and G894T polymorphisms and peripheral blood eNOS mRNA levels in Sickle Cell Disease
por: Armenis, Iakovos, et al.
Publicado: (2016)

AB037. Icariside II improves human cavernous endothelial cells function by regulating miR-155/eNOS signal pathway
por: Guan, Ruili, et al.
Publicado: (2016)

Kallistatin attenuates endothelial senescence by modulating Let‐7g‐mediated miR‐34a‐SIRT1‐eNOS pathway
por: Guo, Youming, et al.
Publicado: (2018)

Knockdown of miR‐423‐5p simultaneously upgrades the eNOS and VEGFa pathways in ADSCs and improves erectile function in diabetic rats
por: Zhou, Jun, et al.
Publicado: (2021)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

Expression of eNOS in kidneys from hypertensive patients
por: Gu, Xin, et al.
Publicado: (2010)

Frequency of eNOS polymorphisms in the Colombian general population
por: Serrano, Norma C, et al.
Publicado: (2010)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

PGC-1α dictates endothelial function through regulation of eNOS expression
por: Craige, Siobhan M., et al.
Publicado: (2016)

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition
por: Chen, Zhenlong, et al.
Publicado: (2012)

Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself
por: Hocher, Berthold, et al.
Publicado: (2022)

sMEK1 inhibits endothelial cell proliferation by attenuating VEGFR-2-dependent-Akt/eNOS/HIF-1α signaling pathways
por: Kim, Boh-Ram, et al.
Publicado: (2015)

Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by (1)H NMR spectroscopy
por: Fernandez Diaz-Rullo, Fernando, et al.
Publicado: (2017)

Recipient iNOS but Not eNOS Deficiency Reduces Luminal Narrowing in Tracheal Allografts
por: Minamoto, Kanji, et al.
Publicado: (2002)

Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
por: Morsy, Mohamed A., et al.
Publicado: (2014)

Effects of dietary l-arginine or N-carbamylglutamate supplementation during late gestation of sows on the miR-15b/16, miR-221/222, VEGFA and eNOS expression in umbilical vein
por: Liu, X. D., et al.
Publicado: (2011)

Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways
por: Zhang, Song, et al.
Publicado: (2019)

Regulation of miRNAs by Natural Antioxidants in Cardiovascular Diseases: Focus on SIRT1 and eNOS
por: Lee, Yunna, et al.
Publicado: (2021)

miR-1226-3p Promotes eNOS Expression of Pulmonary Arterial Endothelial Cells to Mitigate Hypertension in Rats via Targeting Profilin-1
por: Jian, Jie, et al.
Publicado: (2021)

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency
por: Gomaraschi, Monica, et al.
Publicado: (2014)

eNOS Gene Variants and the Risk of Premature Myocardial Infarction
por: Zigra, Aggeliki-Maria, et al.
Publicado: (2013)

eNOS Gene Variant in Patients with Coronary Artery Disease
por: Abolhalaj, Milad, et al.
Publicado: (2013)

Circ-100290 Positively Regulates Angiogenesis Induced by Conditioned Medium of Human Amnion-Derived Mesenchymal Stem Cells Through miR-449a/eNOS and miR-449a/VEGFA Axes
por: Tang, Zichun, et al.
Publicado: (2020)

Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
por: Bucci, Mariarosaria, et al.
Publicado: (2013)

eNOS/iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia
por: Du, L, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_004f47svu49tg7t0pb39936rpa