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Estimating the basic reproduction number of a pathogen in a single host when only a single founder successfully infects

If viruses or other pathogens infect a single host, the outcome of infection may depend on the initial basic reproduction number R(0), the expected number of host cells infected by a single infected cell. This article shows that sometimes, phylogenetic models can estimate the initial R(0), using onl...

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Detalles Bibliográficos
Autores principales: Patel, Vruj, Spouge, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953795/
https://www.ncbi.nlm.nih.gov/pubmed/31923263
http://dx.doi.org/10.1371/journal.pone.0227127